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Home > Research and Activities > Laboratory of Vaccine Materials

Laboratory of Vaccine Materials

1. Members

Project leader Jun Kunisawa
Senior researcher Takahiro Nagatake
Project researcher Hidehiko Suzuki, Ayu Matsunaga
Visiting Researcher Koji Hosomi, Ichiro Takahashi, Takahiro Adachi, Yosuke Kurashima, Keisuke Tachibana, Yuta Tsunematsu, Michio Sato, Sino Yamasaki, Chika Honda, Rie Tomizawa, Chiaki Matsuzaki, Yoshiko Aihara, Yuichiro Hirayama, Mariko Kamioka, Yuka Sasakawa, Yumi Itoh, Akari Kominami, Michiyo Abe, Keiichi Ishido, Yasunori Yonejima, Hiroshi Horita, Toshio Fujimura, Hidenori Shimizu, Shigeki Okamoto, Mayu Saito, Yoshimasa Oka, Chiaki Tomimoto, Sotaro Hamakita, Satoru Ishikawa, Shota Kajiyama, Hiroji Kitahira, Yuki Shimada, Kanjyun Matsuoka, Sayaka Oki, Noriyuki Ikeda, Tetsuo Takagi, Akiko Ogawa, Koji Masuda, Shogo Tsujino, Osamu Kanauchi, Masaya Kanayama, Yasuyuki Tomita, Yukiko Kato, Koichiro Suzuki, Hitomi Asazawa, Tsubasa Matsuoka, Mao Nishimura, Yuka Goto
Research Trainee Natsuko Matsumoto, Aiko Yonezawa, Yasuharu Takahashi, Tokiko Tabata, Takehiro Otoshi, Haruna Sasaki, Yuki Miyoshi, Akemi Hirasawa, Rio Kuroda, Kazunari Yamaoka, Shinichi Maeda, Maho Nakada, Atsuro Minami, Ryota Tamafune, Fumi Higashiguchi
Graduate Student Soichiro Hirata, Azusa Saika, Kento Sawane, Lan Huangwenxian, Yuki Shibata, Wan Yunru, Ken Yoshii
Technical Assistant Sakiko Morimoto, Tomomi Nishino, Yoko Tojima, Mari Furuta
Secretary Takako Minamoto

2. Background and Objectives

Materials such as antigen delivery system, adjuvant, immunomodulator are required for the development of vaccines, immunotherapy, and functional foods. The aims of Laboratory of Vaccine Materials are to understand the host immunity controlled by gut environment such as commensal or pathogenic microorganisms and diets and to apply the basic findings to the development of vaccines, immunotherapy, and functional foods.

3. Overview of our research

1. The development of effective vaccine materials based on the unique functions of commensal and pathogenic microorganisms

This project aims to reveal the immunological function of commensal and pathogenic bacteria (e.g., Alcaligenes and C. perfringens) and apply their functional molecules to vaccine materials (e.g., vaccine delivery and adjuvant) to promote active or quiescent immunity without disrupting immunological homeostasis.

2. Elucidation of unique features of mucosal immune system controlled by diets

As diets, the lab focuses on oils and vitamins et al. As the basic research, we have examined immunologic functions of dietary oils as a source of lipid mediators and have identified some good mediators for the control of allergic and inflammatory diseases. We are currently trying to translate them to the development of functional foods and medicine. In vitamin project, we have reported specific functions of some vitamins (vitamin A and B family) as a key regulator of particular type of immune responses and are currently expanding the studies to examine other vitamin-mediated immunologic functions.

Laboratory of Vaccine Materials

Website http://www.nibiohn.go.jp/vaccine_material_project/english/
E-mail kunisawa[at]nibiohn.go.jp

Research and Activities

  • List

    NIBIO

    Laboratory of Immune Signal
    Laboratory of Adjuvant Innovation
    Laboratory of Mockup Vaccine
    Laboratory of Vaccine Materials
    Laboratory of Infectious Diseases and Immunity
    Laboratory of Stem Cell Regulation
    Laboratory of Hepatocyte Regulation
    Laboratory of Toxicogenomics Informatics
    Laboratory of Biopharmaceutical Research
    Laboratory of Bioinformatics
    Laboratory of Proteome Research
    Laboratory of Nuclear Transport Dynamics
    Laboratory of Rare Disease Biospecimen
    Laboratory of Cell Cultures
    Laboratory of Animal Models for Human Diseases
    Platform of Therapeutics for Rare Disease
    Office of Policy and Ethics Research
    Center for Drug Design Research
    Research Center for Medicinal Plant Resources
    Tsukuba Primate Research Center
    Department of Bioresources for Drug Discovery
    Section of Laboratory Equipment
    Department of Research and Development
    KAGAMI Project
    Laboratory of Immunosenescence

    NIHN

    Department of Nutritional Epidemiology
    Section of the National Health and Nutrition Survey
    Section of the Dietary Reference Intakes
    Department of Health Promotion and Exercise
    Section of Exercise Guideline
    Section of Physical Activity Assessment
    Department of Clinical Nutrition
    Section of Metabolic Syndrome
    Section of Nutritional Therapy
    Department of Nutritional Education
    Section of Nutritional Care and Management
    Section of Shokuiku
    Department of Nutritional Science
    Section of Major Nutrients
    Section of Energy Metabolism
    Department of Food Function and Labeling
    Section of Food Component Analysis
    Section of Food and Nutrition Labeling
    Section of Food Function
    Information Center
    Section of Information Network of Health Food
    Section of Nutrition Informatics and Technology
    Center for International Collaboration and Partnership
    Section of International Nutrition Research and Development
    Section of Biostatistical Research
    Section of Training and Partnership

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