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Home > Research and Activities > Laboratory of Vaccine Materials

Laboratory of Vaccine Materials

1. Members

Project Leader KUNISAWA Jun
Senior Researcher HOSOMI Koji
Researcher KAWAI Soichiro, SAIKA Azusa
Research Trainee YOSHII Ken, Sun Xiao, Liu Zilai, ISHIDA Kei,HIFUMI Seiya, HOTTA Masashi
Technical Assistant TOJIMA Yoko, FURUTA Mari, NODE Eri, MORITA Makiko, UCHIYAMA Keita
Secretary MURAKAMI Asako, NAKATSU Aki

2. Background and Objectives

Materials such as antigen delivery system, adjuvant, immunomodulator are required for the development of vaccines, immunotherapy, and functional foods. The aims of Laboratory of Vaccine Materials are to understand the host immunity controlled by gut environment such as commensal or pathogenic microorganisms and diets and to apply the basic findings to the development of vaccines, immunotherapy, and functional foods.

3. Overview of our research

1. The development of effective vaccine materials based on the unique functions of commensal and pathogenic microorganisms

This project aims to reveal the immunological function of commensal and pathogenic bacteria (e.g., Alcaligenes and C. perfringens) and apply their functional molecules to vaccine materials (e.g., vaccine delivery and adjuvant) to promote active or quiescent immunity without disrupting immunological homeostasis.

2. Elucidation of unique features of mucosal immune system controlled by diets

As diets, the lab focuses on oils and vitamins et al. As the basic research, we have examined immunologic functions of dietary oils as a source of lipid mediators and have identified some good mediators for the control of allergic and inflammatory diseases. We are currently trying to translate them to the development of functional foods and medicine. In vitamin project, we have reported specific functions of some vitamins (vitamin A and B family) as a key regulator of particular type of immune responses and are currently expanding the studies to examine other vitamin-mediated immunologic functions.

Laboratory of Vaccine Materials

Website http://www.nibiohn.go.jp/vaccine_material_project/english/
E-mail kunisawa[at]nibiohn.go.jp

Research and Activities

  • List

    NIBIO

    Coordination Office of Research Ethics
    Department of Research and Development
    Center for Rare Disease Research
    Reverse Translational Research Project
    Platform of Therapeutics for Rare Disease
    Laboratory of Rare Disease Information and Resource Library
    Laboratory of Animal Models for Human Diseases
    Center for Vaccine and Adjuvant Research
    Laboratory of Vaccine Materials
    Laboratory of Regulation of intractable Infectious Diseases
    Laboratory of Immunobiologics Evaluation
    Laboratory of Cell Vaccine
    Laboratory of Mockup Vaccine
    Center for Drug Design Research
    Laboratory of Proteomics for Drug Discovery
    Laboratory of Biopharmaceutical Research
    Laboratory of Antibody Design
    Laboratory of XNA Screening and Design
    Laboratory of Medicinal Plant Screening
    Laboratory of Pharmacokinetic Optimization
    Laboratory of Cell Network Regulation
    Laboratory of Bioimaging and Drug Discovery
    Laboratory of Advanced Biopharmaceuticals
    Laboratory of Clinical and Analytical Chemistry
    Artificial Intelligence Center for Health and Biomedical Research
    Laboratory of Bioinformatics
    Laboratory of In silico design
    AI nutrition project
    Laboratory of Toxicogenomics Informatics
    Laboratory of Proteome Research
    Laboratory of Stem Cell Regulation
    Laboratory of Hepatocyte Regulation
    Laboratory of Cell Cultures
    Section of Laboratory Equipment
    Section of Laboratory Animals
    Research Center for Medicinal Plant Resources
    Tsukuba Primate Research Center
    Laboratory of Infectious Diseases and Immunity
    Laboratory of Nuclear Transport Dynamics
    Laboratory of Gut Environmental System
    KAGAMI Project
    Laboratory of Immunosenescence

    NIHN

    Department of Nutritional Epidemiology and Shokuiku
    Section of the National Health and Nutrition Survey
    Section of Shokuiku
    Section of Dietary Guidelines
    Department of Physical Activity Research
    Section of Behavioral Physiology
    Section of Exercise Guideline
    Section of Healthy Longevity Researches
    Department of Clinical Nutrition
    Section of Nutritional Therapy
    Department of Nutrition and Metabolism
    Section of Chrononutrition
    Section of Energy Metabolism
    Department of Food Function and Labeling
    Section of Food Component Analysis
    Section of Food Safety and Function
    Section of Information Network of Health Food
    International Center for Nutrition and Information
    Section of International Nutrition Strategy
    Section of Population Health Metrics
    Section of Global Disaster Nutrition
    AI Nutrition Research team
    Section of Research Collaboration and Partnership

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