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20212020201920182017201620152014201320122011201020092008200720062005以前

  2012年度
受賞歴   
  角田慎一:


  長野一也:

日本DDS学会奨励賞 (基礎研究)
タンパク質工学によるDDSを駆使した免疫応答制御法に関する研究.

日本DDS学会学術集会優秀発表賞
がん個別化医療のためのシスプラチン感受性マーカー蛋白質の探索.
原著論文
  鎌田 春彦

Kitagaki M., Isoda K., Kamada H., Kobayashi T., Tsunoda S., Tsutsumi Y., Niida T., Kujiraoka T., Ishigami N., Ishihara M., Matsubara O., Ohsuzu F., Kikuchi M.
Novel TNF-alpha receptor-1 antagonist treatment attenuates arterial inflammation and intimal hyperplasia in mice.
J. Atheroscler. Thromb., 19(1):36-46, 2012.[PubMed]


Nabeshi H., Yoshikawa T., Matsuyama K., Nakazato Y., Arimori A., Isobe M., Tochigi S., Kondoh S., Hirai T., Akase T., Yamashita T., Yamashita K., Yoshida T., Nagano K., Abe Y., Yoshioka Y., Kamada H., Imazawa T., Kondoh M., Yagi K., Mayumi T., Itoh N., Tsunoda S., Tsutsumi Y.
Amorphous nanosilicas induce consumptive coagulopathy after systemic exposure.
Nanotechnol., 23:1-8, 2012.[PubMed]

Hirai T., Yoshikawa T., Nabeshi H., Yoshida T., Tochigi S., Ichihashi K., Uji M., Akase T., Nagano K., Abe Y., Kamada H., Itoh N., Tsunoda S., Yoshioka Y., Tsutsumi Y.
Amorphous silica nanoparticles size-dependently aggravate atopic dermatitis-like skin lesions following an intradermal injection..
Part. Fibre. Toxicol., 9(1):3, 2012.[PubMed]


Yamashita T., Okamura T., Nagano K., Imai S., Abe Y., Nabeshi H., Yoshikawa T.Yoshioka Y., Kamada H., Tsutsumi Y., Tsunoda S.
Rho GDP-dissociation inhibitor alpha is associated with cancer metastasis in colon and prostate cancer.
Pharmazie., 67(3): 253-255, 2012.[PubMed]


Yamashita T., Nagano K., Kanasaki S., Maeda Y., Furuya T., Inoue M., Nabeshi H., Yoshikawa T., Yoshioka Y., Itoh N., Abe Y., Kamada H., Tsutsumi Y., Tsunoda S.
Annexin A4 is a possible biomarker for cisplatin susceptibility of malignant mesothelioma cells.
Biochem. Biophys. Res. Commun., 421(1):140-4,2012. [PubMed]

Morishita Y., Yoshioka Y., Satoh H., Nojiri N., Nagano K., Abe Y., Kamada H., Tsunoda S., Nabeshi H., Yoshikawa T., Tsutsumi Y.
Distribution and histological effects of intravenously administered amorphous nanosilica particles in the testes of mice.
Biochem. Biophys. Res. Commun., 420(2):297-301,2012.[PubMed]

Hirai T., Yoshikawa T., Nabeshi H., Yoshida T., Tochigi S., Uji M., Ichihashi K., Akase T., Nagano K., Abe Y., Kamada H., Tsunoda S., Yoshioka Y., Itoh N., Tsutsumi Y.
Dermal absorption of amorphous nanosilica particles after topical exposure for three days.,
Pharmazie.,67(8):742-3,2012.[PubMed]

Yoshida T., Matsuyama K., Yoshikawa T., Nabeshi H., Nakazato Y., Tochigi S., Hirai T., Uji M., Ichihashi K., Akase T., Nagano K., Abe Y., Kamada H., Tsunoda S., Yoshioka Y., Itoh N., Tsutsumi Y. : Amorphous nanosilica particles induce ROS generation in Langerhans cells.,
Pharmazie., 67(8):740-1, 2012.[PubMed]

Nagano T., Yoshioka Y., Higashisaka K., Kunieda A., Hata K., Nagano K., Abe Y., Kamada H., Tsunoda S., Nabeshi H., Yoshikawa T., Tsutsumi Y.
Potential of acute-phase proteins as biomarkers for sub-nano platinum exposure.,
Pharmazie, 67(11):958-9, 2012.[PubMed]

Hirai T., Yoshioka Y.,Takahashi H., Ichihashi K., Yoshida T., Tochigi S., Nagano K., Abe Y., KamadaH., Tsunoda S., Nabeshi H., Yoshikawa T., Tsutsumi Y.
Amorphous silica nanoparticles enhance cross-presentation in murine dendritic cells.,
Biochem. Biophys.
Res. Commun., 427(3):553-6, 2012.[PubMed]

Higashisaka K., Yoshioka Y., Yamashita K., Morishita Y., Pan H., Ogura T., Nagano T., Kunieda A., Nagano K., Abe Y., Kamada H., Tsunoda S., Nabeshi H., Yoshikawa T., Tsutsumi Y.
Hemopexin as biomarkers for analyzing the biological responses associated with exposure to silica nanoparticles.,
Nanoscale Res. Lett., 7(1):555, 2012.[PubMed]

Yoshida T., Yoshioka Y., Matsuyama K., Nakazato Y., Tochigi S., Hirai T., Kondoh S., Nagano K., Abe Y., Kamada H., Tsunoda S., Nabeshi H., Yoshikawa T., Tsutsumi Y.
Surface modification of amorphous nanosilica particles suppresses nanosilica-induced cytotoxicity, ROS generation, and DNA damage in various mammalian cells., Biochem. Biophys.
Res. Commun., 427(4):748-52, 2012.[PubMed]

Nagano K., Okamura T., Yamashita T., Kanasaki S., Maeda Y., Inoue M., Abe Y., Kamada H., Tsutsumi Y., Tsunoda S.
Expression of Rho GDP dissociation inhibitor correlates positively with lymph node metastasis in colorectal cancer.,
Eur. J. Cancer.
, 48(5): S64, 2012. (Supplement)

Kamada H., Yamashita T., Kanasaki S., Maeda Y., Inoue M., Nagano K., Abe Y., Tsutsumi Y., Tsunoda S.
Detection of drug-target proteins on tumor-derived exosomes by ELISA using anti-CD81 antibodies.,
Eur. J. Cancer., 48(5): S238, 2012. (Supplement)

永田 諭志
Phung Y, Gao W, Man YG, Nagata S, Ho M (2012) High-affinity monoclonal antibodies to cell surface tumor antigen glypican-3 generated through a combination of peptide immunization and flow cytometry screening, MAbs 4, 592-599.[PubMed]

Hashimoto EH, Kamogae M, Vanzella TB, Mara I, Cólus S, Paula A, Rodrigues F, Bracarense L, Bittencourt-Oliveira CM, Itano E, Kuroda EK, Kato H, Nagata S, Ueno Y, Harada K, Hrooka, EY (2012) Biomonitoring of Microcystin and Aflatoxin Co-Occurrence in Aquaculture Using Immunohistochemistry and Genotoxicity Assays, Brazilian Archives of Biology and Technology 55, 151-159.
in press.

Dement-Brown J, Newton CS, Ise T, Damdinsuren B, Nagata S, Tolnay M. (2012) Fc receptor-like 5 promotes B cell proliferation and drives the development of cells displaying switched isotypes The Journal of Leukocyte Biology 91, 59-67.[PubMed]